second you have propulsion here are your options:

Conventional rockets these are extremely inefficient and are not even high thrust compared to other methods so absolute GARBAGE

Nuclear fission or fusion these have much higher thrust and efficiency and are our best shot for in the near future

Project starshot soot a giant laser at a tiny spacecraft and you can get it moving really fast however you have no way to slow it down and it cannot be more than a few grams in mass

antimatter drive matter-antimatter annihilation converts 100% of the mass to energy making it unbeatable when it comes to efficiency but it still takes a long time to get to Alpha Centauri

WARP DRIVE (yes really) it is possible to instead of moving yourself move the space around you faster than light while still technically having a speed of "zero" however you would need in order to fuel your ship antimatter or a tiny black hole (using hawking radiation)